Topic

Nutrition & body composition

Diet, muscle, and fat — the levers of body composition and the evidence behind the protocols that promise to move them.

Body composition is where nutrition, training, and increasingly pharmacology intersect. This hub covers the evidence behind the diets, protocols, and compounds aimed at changing the ratio of muscle to fat, and the outcomes that actually track health.

Publications on this topic

Evidence Review18 min read

Lean Mass During GLP-1 Weight Loss

Rapid GLP-1 and GLP-1/GIP weight loss reduces lean mass as well as fat — but so does any large weight loss, and 'lean mass' on a body scan is not contractile muscle. This explainer reports the exact DEXA-substudy percentages from SURMOUNT-1 and STEP 1, separates the expected adaptation to a smaller body from a genuine clinical concern, and weighs what resistance training and adequate protein can preserve against what they cannot.

August 24, 2026Read

Nutrition & body composition

Publications on this topic

Lean Mass During GLP-1 Weight Loss

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